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In animal studies.flutamide demonstrates potent antiandrogenic eulexin sale. It exerts its antiandrogenic action by inhibiting androgen uptake and/or by inhibiting nuclear binding of androgen in target tissues or both. Prostatic carcinoma is known to be androgen-sensitive and responds to treatment that counteracts the effect of androgen and/or removes the source of androgen.eg.castration. Elevations of plasma testosterone and estradiol levels have been noted following flutamide administration.
The most frequently reported (greater than 5%) adverse experiences during treatment with EULEXIN (flutamide) Capsules in combination with an LHRH agonist are listed in the table below. For comparison.adverse experiences seen with an LHRH agonist and placebo are also listed in the following table.
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