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Carbamazepine.Phenobarbital.Phenytoin . While not systematically studied.these drugs may induce the metabolism of bupropion and may decrease bupropion exposure [see CLINICAL PHARMACOLOGY ]. If bupropion is used concomitantly with a CYP inducer.it may be necessary to increase the dose of bupropion.but the maximum recommended dose should not be exceeded.

Jay W. Marks.MD.is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

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bupropion hydrobromide aplenzin and bupropion hydrochloride budeprion sr, budeprion xl, buproban, wellbutrin, wellbutrin sr, and wellbutrin xl aren t approved for smoking cessation treatment, but bupropion hydrochloride under the names of buproban and zyban is approved for this use.